Apnea Positive Pressure Long-Term Efficacy Study
More than 15 million Americans have been diagnosed with Obstructive Sleep Apnea (OSA). Common symptoms of this sleep disorder include loud snoring, fatigue, daytime sleepiness, restless sleep, and choking or gasping noises during sleep. Additionally, individuals with OSA often have a hard time concentrating, experience reduced memory, and have greater difficulty learning new tasks.
Continuous Positive Airway Pressure (CPAP) is the most common treatment of OSA. This therapy requires sleeping with a mask, which is worn over the nse and connected to a machine through a flexible hose. The CPAP machine produces heated and humidified air, which is blown gently into the back of the throat. This air holds the throat open during sleep, so the individual can breathe normally.
The Arizona Respiratory Center is one of five sleep disorder centers nationwide participating in the Apnea Positive Pressure Long-Term Efficacy Study (APPLES) which is designed to measure the effectiveness of CPAP treatment for OSA. The study is funded by a $14.1 million grant from the National Institutes of Health (NIH). A total of 1100 subjects will be enrolled at five clinical centers.
The primary goal of the study is to test the hypothesis that CPAP therapy results in significant, stable, and long-term benefits to neurocogintive function, mood, sleepiness, and quality of life in patients with OSAS.
- Visit the APPLES website for more information.
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